Stanozolol solo (Winstrol) is a drug from the group of anabolic steroids. It is a modified analogue of dihydrotestosterone (the active form of testosterone produced by the human body).
This substance was originally developed to increase muscle mass in animals, but soon the FDA (Food and Drug Administration) approved its use in humans.
At the moment, Winstrol and its derivatives are officially recognized as doping. Their use on the territory of the Russian Federation is limited.
Stanozolol: description and mechanism of action
By its chemical nature, Winstrol Solo is a progesterone antagonist - a peptide that affects sexual function, pregnancy and human embryogenesis. It is an intermediate product in the production of sex hormones and glucocorticosteroids.
The main link in the mechanism of action of stanozolol is penetration into the cell nucleus. There it increases the synthesis of genetic material (DNA and RNA) and proteins. This leads to increased tissue respiration, oxidative phosphorylation processes, as well as the production and deposition of ATP (Adenosine triphosphate is the main energy substrate of the cell).
These effects lead to the activation of anabolic and inhibition of catabolic reactions.
Composition and chemical formula
In terms of its chemical structure, Stanozolol is an analogue of human dihydrotestosterone (differing in the carbonyl group at the 3rd position replaced by +3,2-pyrazole and the methyl group at the 17α-position). This molecular structure makes Winstrol a drug with high bioavailability (most of the administered dose enters the bloodstream, producing effects).
The drug is metabolized primarily by the liver, so strict dose control is required for diseases of this organ. The half-life ranges from 10 to 24 hours. First of all, this indicator is influenced by the form in which Winstrol is located (injection - 4-5, tablet - 18-24 hours). Winstrol is excreted from the body in urine and bile.
How does the substance work?
Stanozolol has an effect on all types of metabolic processes, including energy, electrolyte, and hormonal profiles.
Some effects of Winstrol:
- anabolic effect;
- influence on the metabolism of calcium and phosphorus;
- increased erythropoiesis;
- androgenic activity.
Winstrol and other drugs in this group have anabolic activity. This is primarily due to increased synthesis of proteins and ATP. Active assembly of peptide chains leads to a noticeable increase in muscle mass. The increased content of ATP in the cell has a beneficial effect on the endurance and strength of the athlete.
Also, many researchers claim that Stanozolol has a fat-burning effect. This significantly improves the condition of the muscles and relief. These effects explain the widespread use of Winstrol in bodybuilding.
The use of stanozolol alone promotes the deposition of calcium in the bones. There is also an increase in the content of nitrogen, sulfur and phosphorus in the body due to protein molecules.
Winstrol affects hematopoiesis (blood formation). It increases the synthesis of erythropoietin in the kidneys, which leads to increased production of red blood cells (RBCs).
Stanozolol has androgenic activity. In men, this can lead to disruption of endogenous testosterone production. As for girls and women of childbearing age, it is necessary to refrain from taking this drug or use the minimum dose.
Excessive amounts of androgens can lead to reproductive dysfunction and the development of secondary sexual characteristics of the male type.
Correct combination
In practice, various courses of Winstrol are used. Let's look at each of them in detail. It is worth noting right away that strength courses using Winstrol do not exist. This is associated with an increased risk of joint injury or muscle tear.
For newbies
Beginning athletes should take Stanozolol or Winstrol tablets for 6-8 weeks. The daily dose should be no more than 40 mg. During the course, you can “get dry” by combining the drug with diet and training, or increase up to 4 kg of muscle mass.
To increase weight
In rare cases, girls can take injectable Winstrol 50 mg, alternating it with the same dose of propionate. The duration of this course is from 6 to 8 weeks. In all other cases, preference should be given to tablets.
For men, a course of oxandralone Winstrol and propionate is more suitable. The dose of each drug is 50 mg. They should be taken alternating every other day. The duration of the course, as for girls, is from 6 to 8 weeks.
To gain weight, you can resort to classic courses:
- methane with Winstrol;
- Deca with Winstrol.
Deca dosage ranges from 200 to 600 mg per week. Methane should be taken in the same way as in a solo course. Winstrol dosage is 50 mg per day. The duration of the course is from 6 to 8 weeks.
For drying
For the drying process, you can combine Winstrol with Primobolan. The dose of Winstrol is 50 mg per day. Primobolan should be taken 100-300 mg per week. Moreover, the weekly norm can be pierced at a time or divided into 2-3 times. Essentially, it doesn't matter.
Release form
Stanozolol solo is available in two forms:
- injection;
- oral tablet forms.
Injections and tablets have some differences in metabolism, speed of onset and duration of action.
Injections
This form is an aqueous solution of the active substance in ampoules. Injectable Stanozolol is represented on the market by the following drugs:
- Stromba;
- Winstrol Depot;
- veterinary drugs.
The average dose is 50 mg/ml (in veterinary drugs it is about 100 mg/ml). The drug is administered by intramuscular injection (preferably injected into the buttock or thigh). On average, depending on the purpose, a course of taking Winstrol lasts about a week.
Advantages of parenteral forms:
- high bioavailability;
- quick effect;
- To achieve results, smaller doses are required, which reduces the toxicity of the drug.
Flaws:
- difficulty of administration;
- soreness.
Pills
Stanozolol tablets are popular among athletes.
Important! The dose contained in the solution is much higher than that of tablet analogues. Therefore, in order for a sufficient amount of the active substance to enter the bloodstream, it is necessary to take from 10 to 30 tablets per day. Moreover, all non-injectable forms are metabolized in the liver, which reduces the bioavailability of the drug.
Benefits of Winstrol tablets:
- ease of administration;
- painlessness.
Flaws:
- you need to take a large number of tablets;
- low effect due to hepatic transformation;
- side effects from the gastrointestinal tract - abdominal pain, nausea, diarrhea, toxic liver damage.
Instructions for use
Stanozolol can be purchased in oral and injection forms. When administered intramuscularly, the activity of the steroid increases by 1.5 times. Depending on the effect that the athlete wants to achieve, a combined course of Stanozolol is drawn up. In order to minimize side effects, hepatoprotectors, supplements for joints and ligaments are taken along with the substance. Post-cycle therapy (PCT), which normalizes the functioning of the hormonal system, is mandatory.
When the first signs of virilization appear in women (acne, clitoromegaly, voice changes), the course must be interrupted. Clinical trials have shown that professional athletes can take 10-20 mg of the substance per day to increase the anaerobic threshold and increase the reduction of fat deposits. Beginning athletes to improve the quality of muscle mass will have to consume up to 50 mg of Stanozolol per day to achieve similar results. The dosage should be selected individually by the doctor based on tests.
The toxicity of the drug to the liver is minimal. A healthy person will be able to consume up to 900 mg per week without any serious consequences for the body. If pain occurs in the liver area during the course, you can drink Holosas. This remedy promotes the outflow of bile and will accelerate the removal of anabolic steroids from the body. If the pain does not go away after consuming Holosas, you should consult a doctor and interrupt therapy.
Stanozolol tablets
Patients who have never taken anabolic steroids begin the course with a minimum daily dose of 10 mg. In order to achieve maximum effect, it is recommended to take Stanozolol tablets on an empty stomach. If there are no side effects, after a couple of days the dosage is increased by 5 mg, gradually bringing it to 50 mg/day. The minimum duration of the course is 5 weeks, and the maximum is 8.
Injections
Athletes practice intramuscular administration of the substance when gaining muscle mass. The toxic effect of the injection solution on the liver is 1.5 times stronger than that of tablets. The recommended dosage of the drug is the same as when using tablets. You should not take more than 50 mg per day. In combined courses with methane and other steroids, the amount of substances consumed should not exceed 500 mg in 1 week.
For women
The dosage is calculated by the doctor based on the patient’s body weight and health status. Women are often interested in the fat-burning effect of Stanozolol. It manifests itself with regular training. Stanozolol is not produced separately for women. The total daily amount of the substance should not exceed 15 mg. It is recommended to take the medicine evenly, i.e. 3 times/day 5 mg. Women who are particularly susceptible to anabolic steroids should take no more than 5 mg of the substance/day. The duration of the course is 4-6 weeks. The injection form of the drug is not prescribed to women.
Useful properties of the drug
Stanozolol is one of the most popular steroids. Moreover, it is used not only by bodybuilders and powerlifters who use the drug to gain muscle mass, but also by track and field athletes who need endurance and strength.
Properties of stanozolol:
- promotes not only weight gain, but also improves the quality of the gained mass;
- increases definition and burns subcutaneous fat;
- improves strength and speed performance of athletes.
There is still ongoing debate about the advisability of using stanozolol in women. It is assumed that there is an anti-estrogenic and anti-progestogenic effect, which in theory has an adverse effect on a woman’s reproductive and endocrine system.
Which doctor should I contact?
In order not to seriously worsen your health, it is better to consult with a specialist about which drug causes gynecomastia, the advisability of its use, and you can also be under the supervision of a specialist while taking this type of drug.
An endocrinologist deals with changes in hormonal levels in the body and treatment of hormonal dysfunction.
I, Romanov Georgy Nikitich, am an experienced specialist in the field of endocrinology, I have extensive experience working with athletes who take or have taken steroid drugs. As a specialist, I have more than 20 years of work experience, received a Candidate of Medical Sciences degree, and manage a private clinic.
Anyone can sign up with me for a paid in-person or online consultation, where I will consider your situation, help you make a diagnosis, prescribe treatment and monitor this process.
You can sign up on one of the social networks or messenger listed on this page.
Harm from taking
Every athlete who uses Winstrol for cutting or increasing endurance wonders about its harm. Stanozolol has the most significant negative effect on the liver. It has been proven that oral forms and large doses of the injectable drug can cause toxic hepatitis, which subsequently leads to liver failure.
Stanozolol is also harmful to the kidneys. In large doses, it can provoke the death of nephrons, causing kidney failure.
The drug has a negative effect on the joints. After taking it, pain in large joints and ligament damage are often observed.
In addition, Winstrol significantly affects the lipid spectrum of the blood (increase in low and very low density lipoproteins), which provokes the development of atherosclerosis.
Contraindicated for whom
The use of any hormonal drugs should be treated with caution. Stanozolol is a testosterone derivative, so its effect is extremely unphysiological for women. Men may also experience hormone-related side effects.
Main contraindications for taking Winstrol:
- hypersensitivity to the components of the drug;
- allergic reactions;
- atherosclerosis of the cerebral and coronary arteries;
- prostate diseases (prostatitis, prostate cancer);
- arterial hypertension 3 degrees;
- hormone-dependent diseases in women (breast cancer, ovarian cancer, uterine cancer, dysmenorrhea);
- liver or kidney failure;
- period of pregnancy and lactation;
- childhood.
The use of Winstrol in the presence of any of the conditions described above puts the athlete’s health at risk.
How to avoid gynecomastia on the course
There are several rules that must be followed during the course, however, the appearance of gynecomastia largely depends on a person’s genetic predisposition.
Let's consider the basic rules that must be followed to prevent the occurrence of the disease:
- proper balanced diet - you need to saturate your body with useful micronutrients, maintain the norm and proportions of proteins, fats and carbohydrates;
- before taking medications, it is best to exclude deficiency conditions in the body;
- a well-designed training program, that is, all loads should be normalized and there should be no serious jumps, then the body gets used to it faster and no serious hormonal disruption occurs;
- There are special drugs that to some extent block the adverse effects of steroids, however, they also have their own side effects and the appropriateness of their use is considered by the doctor based on the patient’s medical history.
Dosage and schedule
Before starting the course, you must undergo a complete and thorough medical examination. Particular attention should be paid to biochemical blood tests (levels of liver enzymes, bilirubin, lipid spectrum and kidney function indicators), ultrasound of the abdominal organs, and ECG.
To correctly select the dosage and duration of the course, you must study the instructions for use in detail.
Stanozolol should be started with 30 mg (for oral forms). As a rule, one tablet contains about 30 mg, therefore, the drug must be taken 3 times a day.
If the choice fell on injection forms, then you need to take Winstrol once a day, starting with 50 mg.
The duration of the course varies from 5 to 8 weeks. An important point is to carry out PCT (post-cycle therapy - a set of drugs taken to restore the body after a course of anabolic steroids). It begins 3-4 days after the end of the course of stanozolol.
Safe dosage regimens and general recommendations
There are three main criteria for safe use of steroids by women:
- Type of steroid
- Dosage
- Cycle duration
We've sorted out the safest types of anabolic steroids and their dosages.
Important nuance:
Women are recommended to take steroids “solo”, that is, when the cycle consists of only one drug.
It is not advisable to practice combined courses, when 2 or more types are used simultaneously, due to the 100% guarantee of side effects.
Now it remains to decide on the duration of use.
Ideally, take tests for hormonal levels and general blood biochemistry before starting steroids, every 2-3 weeks of the cycle and 3-5 weeks after the end of the steroid course.
Thanks to these analyses, the optimal duration of one cycle is calculated with minimal negative interventions.
Of course, this requires a specialist who can interpret the results and recommend measures to adjust the steroid course (drugs, dosages, duration of use, plus concomitant medications).
If such a specialist is not at hand, then we focus on the data below. They are approximate, since each girl, due to her individual characteristics, will have a different body reaction to taking steroids.
- One of the popular “female” schemes is 3+3.
The steroid is taken for three weeks, followed by three weeks of rest. Then the cycle is repeated 1-2 more times, after which the rest continues for 2-3 months.
- Another option is to take 4-5 weeks
Longer cycles are undesirable due to the high possibility of side effects.
Exceeding the recommended dose
Exceeding the dose can be intentional or unintentional. The first happens when toxic doses are consumed in order to improve performance.
Unintentional excess of the dose may be the result of negligence (error in selecting the amount of stanozolol, frequency of administration and duration of the course).
Also, an excess of steroids can occur during combination therapy with substances with similar mechanisms of action. Therefore, it is extremely important to monitor the quantity and quality of medications taken.
Toxic effects that occur during overdose:
- drug-induced hepatitis;
- kidney damage;
- atherosclerosis and coronary heart disease;
- arterial hypertension;
- damage to joints and tubular bones;
- decreased function of the sex gonads.
By-effect
Unlike toxic side effects, side effects develop with the usual dosage regimen in predisposed individuals.
The most common symptoms encountered when taking stanozolol are:
- acne (acne);
- alopecia (baldness);
- gynecomastia (growth of mammary glands in men);
- increased levels of liver enzymes;
- increased blood pressure;
- urinary disturbance;
- dysfunction of the gastrointestinal tract;
- dehydration (excessive release of fluid from the body);
- pain in joints and bones;
- suppression of ovarian function;
- suppression of endogenous testosterone production.
What is Stanozolol
The drug is an anabolic steroid synthesized from dihydrotestosterone. Unlike other testosterone derivatives, Stanozolol does not cause a strong androgenic effect, so it is often used by women. In medical practice, the drug is used to normalize protein synthesis and restore the body after extreme exhaustion. In reviews, patients note that short-term use of Stanozolol greatly increases appetite. Distinctive features of the substance:
- activity lasts up to 8 hours;
- complete absence of aromatization (transition to female sex hormones);
- moderate level of liver toxicity;
- acts as an antiprogestogen and antiestrogen;
- removes excess water from the body.
Initially, this anabolic steroid was used in veterinary medicine to increase muscle mass and stimulate the appetite of malnourished animals. In 1962, the drug first appeared in pharmacies. It was intended for the treatment of hereditary angioedema and anemia. In 1970, it began to be actively used on racing horses to increase speed performance, and then the drug began to be used in professional sports.
Analogs
These days, the pharmaceutical market offers a huge number of stanozolol analogues. As a rule, the difference between them is insignificant, because the composition contains one active ingredient.
Parenteral drugs (injections):
- Rexogin (50 mg);
- Stanabol (50 mg);
- Farmastan (50 mg);
- Stanover (50 mg).
Tablet forms:
- Rexobol (10 or 50 mg);
- Strombafort (5 or 10 mg);
- Azolol (5 mg);
- Stanodrol (10 mg);
- Stanos (10 mg).
When taking steroids, you cannot combine drugs from different manufacturers. This will not lead to increased strength and endurance, but may provoke unwanted side effects.
