Steroid anti-inflammatory drugs: instructions for the first-generation

Pharmacological means for weight gain are medications and sports nutrition products that are aimed at activating metabolic processes in the body. Drugs in this category increase the physical endurance of the body, ensure better absorption of nutrients, and stimulate the growth of muscle tissue.

Pharma for weight gain

Medicines and pharmacological agents for weight gain are classified into hormonal ones, as well as those that do not contain a steroid component.

Mass gain pharma helps a bodybuilder gain muscle mass.

Hormonal

Hormonal mass gainers are anabolic steroids, the active components of which are synthetic hormones. These drugs accelerate the growth of lean muscle mass and affect the functions of the endocrine system. The advantage of using these products is that while taking hormonal drugs, it is possible to achieve maximum muscle growth, spending a minimum amount of time on the training process.

The following drugs are distinguished in this category:

• Dexamethasone;
• Oxandrolone;
• Stanozolol;
• Turinabol.

The main disadvantages of using steroid drugs are a large number of side effects in the form of an imbalance of sex hormones, faster wear and tear of internal organs, baldness or abundant hair growth throughout the body.

Non-hormonal

Pharmacology for weight gain without hormonal substances are drugs whose active components are chemical components of synthetic and natural origin. Products in this category also accelerate metabolic processes, promote faster growth of muscle tissue and improve appetite. The advantages of non-hormonal drugs are that they cause minimal side effects.

Most often these are allergic reactions of local manifestation. The disadvantage of these drugs is their slower effect on weight gain. Also, these drugs can cause not only a gain of muscle tissue, but also provoke the formation of fatty deposits.

Non-hormonal drugs include:

• vitamin and mineral complexes;
• alcohol tincture of Manchurian Aralia, Leuzea rhizomes;
• Vinpocetine.

Course for beginners

Let’s make a reservation right away: “newbie” here is meant not in terms of training, but in terms of taking anabolic steroids. In this case, one drug will be enough for the first time.

Consider the following options:

• Oxandrolone (aka Anavar). The "mildest" of all oral steroids. There are practically no side effects - there is no aromatization, the effect on the liver and endogenous testosterone levels is minimal. However, one should not expect a huge effect from the drug. It is suitable only for beginners, for whom such an action will be enough for progress. Recently, difficulties have arisen with purchasing the drug; many counterfeits have appeared on the market, and therefore you need to choose it wisely. Dosage regimen: Course duration – 6-8 weeks. Dosage - 40-60 mg/day . You need to divide it into 2 parts, taking it every 12 hours.
• Turinabol . A more effective drug, similar to the well-known “methane”, but softer and with fewer side effects. Similar to the first steroid, it is available in tablets, has a negative effect on the liver and does not aromatize. It does not retain water in the body, but it helps a lot in gaining weight. Application regimen: Duration – 6-8 weeks. Dosage - 30-50 mg/day . Divided into 2 parts.
• Methandrostenolone (aka methane, danabol). Probably the most commonly used oral steroid. Usually available in tablet form, but recently it has also appeared in injectable form. However, reviews about this product are mixed. It retains water in the body quite strongly, reduces testosterone production, affects the liver and can aromatize. But its effect is stronger than that of the first two drugs. Regimen: Duration – 6-8 weeks. Dosage - 30-40 mg/day . Divided into 2 parts.
• Primobolan (aka methenolone). Available in both tablets and solution, but the second option is more common. It has a fairly “soft” effect. As a rule, it is used in a stack with other drugs, but for a beginner it will be enough for the first course. Along with Anavar, it is the leader in terms of minimal side effects. The injectable form does not harm the liver, does not aromatize, and only slightly suppresses testosterone production. Application regimen: Duration – 8 weeks. Dosage – 400 mg per week (by injection). Can be divided into 2 doses (for example, on Monday and Thursday).
• Testosterone propionate . This is a “short” formula of the main male hormone, that is, the peak of its action is only 1-2 days. Accordingly, the drug will have to be administered every other day (or better even every day to ensure the most even background of the substance). This option as a first course of steroids for mass is more suitable for older athletes whose endogenous testosterone levels are already low. The dosage here is 50-100 mg every other day (or 50 daily). Course duration is 6-8 weeks. It is necessary to take into account that all the side effects from androgenic drugs can already appear here - gynecomastia, acne, suppression of the production of one’s own hormone, etc.

List of the most dangerous anabolic steroids

The practical use of steroids, as well as their clinical use, has shown that the most dangerous anabolic steroids are the following drugs:

• Dinitrophenol;
• Mibolerone (also known as Check-Drops);
• Halostenin;
• EPO;
• Anadrol.

The above anabolic steroids can cause severe side effects, disrupt the functioning of internal organs, the endocrine system, lead to changes in hormonal balance, and liver damage.

Methionine

An amino acid that is an important part of protein. The drug takes part in metabolism, burns fat, synthesizes adrenaline, creatine and a number of other important processes that influence the increase in muscle volume

Daily dosage 1.5 g. daily. Take 3-4 times 30 minutes before meals. The duration of treatment is 10-30 days, after which there is a mandatory break of 14 days.

Side effects may manifest themselves in the form of nausea and vomiting.

The listed list of drugs is legal and is available in all pharmacies. You can take them, but wisely, otherwise instead of the desired effect you will only get a minus!

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What medications should men take?

Men who want to gain muscle mass and have an athletic physique can take the following medications:

• Duphaston;
• Oxandrolone;
• Androil;
• Peritol;
• Dexamethasone;
• Brewer's yeast;
• Glutamic acid.

The above drugs, which promote weight gain, affect the energy balance in the human body and activate lipid, protein and carbohydrate metabolism. For people who have chronic diseases of the heart, pancreas, liver and kidneys, taking these medications is contraindicated.

Riboxin and bodybuilding

In second place on the hit parade is Riboxin, a drug that bodybuilders use for muscle growth and can be bought at a simple pharmacy. The supplement is considered an excellent source of energy, which cells use to build new muscle fibers. Thanks to Riboxin, restoration processes occur with greater intensity, tissues receive energy, and internal systems do not suffer from a lack of oxygen.

The positive aspects of taking Riboxin are:

Ø Plays a key role in the synthesis of proteins and nucleic acid Ø Prevents tissues from starving and lacking oxygen Ø Prevents our heart from contracting coronary disease Ø Positively affects recovery processes Ø Creates a balance in energy processes Ø Controls the work of the heart

Thanks to taking Riboxin, the athlete increases endurance, accelerates the growth of muscle fibers, and strengthens the immune system. Regular use of the drug allows the athlete to stay in the gym longer and recover faster after a hard workout.

Riboxin form and dosage

At the pharmacy, anabolic steroids can be purchased in tablets, solutions and capsules. The price per record is no more than 40 rubles. Ampoules are more expensive, 70-140 rubles, solution 60-150 rubles.

If we talk about tableted Riboxin, athletes take 3-4 tablets 3-4 times a day before meals. To begin with, the normal dose is 1 tablet 3-4 times a day. A unique course of taking Riboxin can take from a month to 90 days. Next, we give the body a rest for 30-45 days and you can re-use the anabolic steroid.

Side effects of Riboxin

Side effects of Riboxin are subtle. This can only include personal intolerance to the drug or those components that are included in the composition. If you take more than what is indicated on the package, you can get an allergic reaction, your heart will start beating faster, your blood pressure will rise.

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What should women take?

Preparations for gaining additional body weight in women contain male and female sex hormones.

In this case, for muscle growth, it is recommended to take the following means:

• Elkar;
• Benzodiazepine;
• Anadrol;
• Duphaston.

The female body is more sensitive to the effects of weight gain drugs. Before taking these medications, you should consult with an endocrinologist and gynecologist.

How do vitamins and minerals work?

Pharmacy drugs are designed to ensure the full functioning of all systems of the human body. To gain muscle mass and quickly recover, it is necessary to promptly remove free radicals from the body that are formed during redox reactions during training exercises.

All this is done by vitamins and minerals, which can be obtained both from food and pharmacological complexes. The list of components is given in the table below.

What is more effective in helping you gain muscle mass: protein or gainer?

Protein and gainer are sports nutrition products that are designed to gain weight. It all depends on what result needs to be achieved. For faster growth of lean muscle mass, it is recommended to use protein, as it contains up to 90% protein.

If a person is very thin and wants to gain not only pronounced body muscles, but also a small percentage of fatty tissue, then in this case it is necessary to use gainers. Preparations in this category contain a balanced formula of proteins and carbohydrates.

Activity of topical corticosteroids

The activity of drugs in this group depends on at least four factors [2, 4].

Release form.

The release form of a local drug is in its own way a “vehicle” that ensures the delivery of active substances deep into the skin. Therefore, the “power” of the topical agent largely depends on its properties.

• Ointments with steroids

  are considered the most effective form of topical corticosteroids. These are water-in-oil emulsions, the high activity of which is due to the ability to form a film on the surface of the skin that is impenetrable to air and moisture and thus provides a “compress effect” - occlusion. As a result, the local concentration and effectiveness of the product increases. But occlusive preparations also have disadvantages: firstly, the skin stops “breathing”, which can contribute to the development of weeping, and secondly, they are inconvenient to apply to the skin of the scalp, chest, etc.

  It is advisable to recommend topical corticosteroids in the form of ointments for the treatment of dry skin diseases.

• Creams

  , unlike ointments, being an “oil in water” emulsion, are not fatty forms. They do not form an occlusive film on the surface of the skin and therefore lack both the disadvantages of ointments and their advantages. GCS creams are less active than steroid ointments.

  Topical corticosteroids in the form of a cream are indicated for acute and subacute inflammation without significant weeping.

• Gels

  - an oil-in-water emulsion with an alcohol base. They liquefy upon contact with skin and have a medium degree of activity.

  It is advisable to recommend gels for the treatment of areas of the body heavily covered with hair.

• Lotions

  , which are aqueous solutions, are considered the least active form of GCS. They evaporate, providing a cooling effect.

  It is advisable to recommend topical GCS in the form of a lotion if it is necessary to treat large areas, as well as areas abundantly supplied with hair follicles.

The salt to which the steroid is bound.

For example, betamethasone exists as valerate, dipropionate, and benzoate, each of which has different potencies.

Active ingredient concentration

The higher the concentration of the active substance, the higher the activity of the drug.

For example, one of the most powerful topical corticosteroids, clobetasol propionate, in the form of an ointment, is approximately 1000 times “more powerful” than the weakest drug in this group, 1% hydrocortisone.

There are two classifications of topical corticosteroids according to the degree of activity - European, which distinguishes 4 classes, and American, in which drugs are divided into 7 classes of activity. In both the first and second, activity was assessed based on vasoconstrictor tests and according to clinical studies.

European classification of topical glucocorticosteroids [3]

American classification of topical corticosteroids [3]

The best sports nutrition for men, women

The best sports nutrition for men and women are pharmacological agents that allow you to gain additional muscle mass and are also relatively safe.

There are the following drugs that have these characteristics:

• Amino X;
• BCAA 97;
• Amino Energy;
• Hard Mass;
• Weight Gainer Blend;
• Mass Effect Revolution;
• Amino Gold.

The above medications should be taken only after a preliminary examination of the body for the possible presence of cardiovascular diseases, chronic damage to liver and kidney tissue.

Pharmacological means for faster weight gain are hormonal and non-hormonal anabolic steroids that speed up metabolism.

Once inside the human body, these medications activate the energy processes of the intracellular space, increase appetite, and ensure high-quality absorption of nutrients. Due to this, rapid development and growth of tissue occurs, and an increase in additional muscle volume is observed.

People who take anabolic steroids but do not exercise may develop obesity. Side effects of medications in this category include allergic reactions, dermatitis, changes in hormonal balance, disturbances in the functioning of the heart, blood vessels, liver and kidney tissues.

Strombaject (stanazolone) Balkan pharm 50 mg/1 ml x 5 pcs.

Price: 850 rub.

Stanozolol is one of the most used steroids, both in bodybuilding and in cyclic sports (for example, athletics), due to its effectiveness and sufficient safety.

Description of the drug:

The anabolic activity of stanozolol is 320% of testosterone. In simple terms, you get more than triple the effect of pure testosterone.

Androgenic activity is very small - about 30% - you will practically not be susceptible to the phenomena of virilization and masculinization. Strombaject from Balkan Pharmaceuticals is not subject to conversion to estrogens. The drug is administered intramuscularly and is therefore not toxic to the liver.

The duration of action of the drug is 1/3 of the day. Balkan Pharmaceuticals produces a quality product at a reasonable price for steroids. Despite some mistrust of users who have not yet taken a course of this anabolic steroid towards manufacturers from the post-Soviet space, we can safely say that the Moldovan product is of sufficient quality.

The company produces anabolic drugs completely legally and, in addition to them, is developing antiviral and anti-infective drugs and antibiotics.

Application:

First of all, it should be noted that Strombaject is water-based and not oil-based, so it has to be injected much more often. When choosing a dosage, you must take into account your professional experience and goals, along with the specifics of the sport. When doing bodybuilding, the optimal course would be up to 8 weeks with daily injections of 50 mg of the drug.

Basically, bodybuilders use stanozolol to gain muscle definition during the drying period. In addition, the drug increases strength indicators. For track and field athletes and athletes of other cyclic sports, a dose of 10 mg/day is recommended.

Precautionary measures:

The main contraindication is individual intolerance to its components. Not recommended for use by minors, women during pregnancy and breastfeeding. In case of renal and liver failure, diseases of the cardiovascular system and breast cancer, use is contraindicated.

Users note the effectiveness of the anabolic Strombaject from Balkan Pharmaceuticals for quickly achieving results in drying the body and increasing muscle definition. The drug has low toxicity and is very effective.

Glycine

This is an amino acid that does not have optical isomers in its structure and is present in many biologically active substances and proteins. The body experiences a particularly acute need for glycine during periods of prolonged stress, after suffering an ischemic stroke, with diseases of the central nervous system and a state of increased excitability, during high physical exertion.

A course of glycine involves taking the drug three times, 1000 milligrams each, that is, 3 grams per day for a month. When an urgent need arises, the course can be repeated. In some people, this amino acid causes increased sensitivity, which becomes an obstacle to the use of the substance.

Glycine consumption:

• improves mood;
• reduces aggression;
• normalizes sleep;
• increases mental activity;
• protects the nervous system from the influence of toxic and harmful substances, including alcohol.

This amino acid can be purchased freely. It is sold through pharmacies in packages of 30 tablets with a total weight of 250 milligrams. One pack costs about 50 rubles. The main purpose of glycine is to stimulate brain activity. Athletes also often resort to taking this amino acid.

Amino acids. Glycine. Real effects. Sedation and blood pressure

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Enzymes

Enzymes promote good absorption of beneficial components from the food consumed, which is why this class of drugs is especially popular among athletes. Calories enter the body in sufficient volume, since the substances are completely broken down and absorbed into the blood. Among these drugs are the following:

1. Panzinorm forte

This drug is suitable for athletes whose work is aimed at building muscle mass. In this case, the body receives a lot of solid protein food, and enzymes contribute to its rapid digestion. The components of the drug are extract of the stomach mucosa of cattle, pancreatin and bile extract.

The drug should be taken while eating food, 1 tablet. three times a day. The price is 110 rubles.

1. Festal

This enzyme preparation promotes thorough digestion of proteins, fats and carbohydrates. It consists of pancreatin, bile extract and hemicellulase enzyme, promoting the absorption of heavy and plant foods. The drug is taken three times a day in the amount of 1 tablet after meals. The price of a package of 20 tablets can reach 145 rubles.

For joint pain

In the complex treatment of joint pain, painkillers are used. Pain in diseases of the musculoskeletal system is often unbearable, so it is impossible to do without medications. The most effective painkillers for joint pain belong to the pharmacological group NSAIDs:

1. Coxib. Available in capsules. The medicine works best in the treatment of osteoarthritis and arthritis.
2. Arcoxia. Prescribed for the symptomatic treatment of osteoarthritis, ankylosing spondylitis, gouty arthritis. The drug is effective after dental surgery.
3. Brufen. Indicated for damage to tendons and ligaments, inflammation of joints of various origins, feverish conditions, lumbago, after sports injuries and accidents.

Find out how to choose painkillers for joint pain.

Every person experiences back pain. The modern pharmaceutical industry does not stand still, and every year it produces the most effective medications that help fight pain. Popular painkillers for back pain:

1. Revmador. A strong pain reliever from the group of non-narcotic analgesics. Used when degenerative diseases of the spine and joints are accompanied by pain.
2. Finalgel. Classification – NSAIDs. Intended for local use during inflammatory diseases of the joints and back, sprains, injuries (closed) of the musculoskeletal system.
3. Phentatine. A narcotic used to treat unbearable pain. Available in the form of crystalline powder. Intended for subcutaneous injections.