Long-acting testosterone: 10 years of journey from research to medical practice. VII International Congress ISSAM “From treatment to prevention: from hormonophobia to hormonophilia”

Testosterone is one of the significant hormones in the human body, which affects our general condition and acts as a regulator of various processes, both in the hormonal system and is involved in metabolism. A deficiency of this hormone leads to various negative consequences from the immune and endocrine systems, which negatively affects overall well-being, which is accompanied by a drop in mood, irritability, weakness, destruction of muscle tissue, and even leads to various disorders in the musculoskeletal system. Therefore, this hormone is used in medical practice, and has also gained popularity in sports since the mid-20th century.

Athletes are familiar with sports pharmacology firsthand. When used correctly, steroids will accelerate muscle growth, increase strength, endurance, and with their help you can achieve greater reduction of fat deposits. But you should not take these drugs without the appropriate knowledge. Today we will talk about testosterone propionate, describe its advantages and disadvantages.

Testosterone propionate[edit | edit code]

Yuzhakov Anton Testosterone description of the drug

Yuzhakov Anton TESTOSTERONE PROPIONATE HOW TO CORRECTLY EXIT THE PROPIONATE COURSE

Yuzhakov Anton FIRST COURSE. COMPILATION, SELECTION OF DOSES, CONTROL OF ANALYSIS.

Testosterone propionate (Ukraine) Propionate from Gerth Pharmaceuticals (volume 10ml, 100mg/ml)

Testosterone propionate

- one of the most popular steroids in bodybuilding. Testosterone propionate is intended for the development of muscle mass and strength, but due to the nature of its action, it is more often used during the drying period. It is one of the testosterone esters. Among the main modern manufacturers of propionate are BP (Balkan Pharmaceuticals), Magnus Pharmaceuticals, Swiss Remedies, Farmakom, Indian Testopin from BM Pharmaceuticals, Ukrainian Testosterone propionate from Farmak, English Verormone from Nordic, Testoger P from Gerth Pharmaceuticals and some others.

How much testosterone propionate can you gain?

As mentioned above, using “propik” for mass gain is not rational.

During the drying process, we work to reduce the percentage of body fat using a caloric deficit in the diet. Therefore, during the drying process, weight gain is, in principle, not possible.

But if you still love “sado-maso”))) and decide to use propik to gain muscle mass, then you should know and understand that no one can accurately predict how much you will gain.

Everyone is different. They have different genetics, metabolism, etc. In addition, the key factor in gaining weight during the cycle is nutrition.

You can “pour” testosterone into yourself in grams, but you won’t gain it unless you create a calorie surplus.

Therefore, if someone confidently tells you some “numbers”, you should know that this is an amateur who does not understand anything about this issue.

Historical background[edit | edit code]

Testosterone propionate was discovered in 1936 and was introduced for medical use in 1937. [1][2] It was the first testosterone ester to be sold and was the main form of testosterone used in medicine until 1960.[3]

Steroid profile[edit | edit code]

Testosterone is a hormone that serves as the main molecule for most hormonal (androgenic) drugs. By changing the testosterone molecule (adding or removing atoms), one or another drug is synthesized. So, for example, testosterone propionate is a testosterone molecule to which a propionic acid ester is attached; it is this that determines the pharmacological properties and features of the action of this substance.

• Anabolic activity - 100% of testosterone
• Androgenic activity - 100% of testosterone (high)
• Aromatization (conversion into estrogens) - high (there is a need for antiestrogens)
• Suppression of the hypothalamic-pituitary-testicular axis is pronounced
• Method of administration: injections
• Duration of action - 2-3 days
• The half-life and MRT (IM) are 0.8 days[4] and 1.5 days, respectively[5][6].
• The peak activity of propionate occurs on the day of injection and gradually decreases within 24–36 hours after injection.[7][8]
• Detection time - 40-60 days

Why is testosterone propionate harmful?

The question is most likely about the side effects of propionate, which we will discuss below.

You must understand that any medical drug has side effects, and it’s easier to count on your fingers those drugs that have “no side effects.” (I have never seen such drugs in my practice)

And when it comes to steroids and the side effects of their use, then real hysteria and “trash” begins.

Very often, even qualified doctors who have not delved into the topic of AS are captive of public stereotypes about the “terrible harm” of steroids.

And what heartbreaking stories about the side effects of AS can be found on the Internet...

Someone’s “liver fell off”, “the kidneys stopped working”...

I will say this, all the horror stories that you may have heard about the dangers of steroids are a complete exaggeration.

For example, regular aspirin will give a huge head start to propionate and other AS in terms of side effects. But we easily take aspirin, without thinking about its potential harm, because it is a common drug for us.

But you should know that, according to statistics, in the United States, which is the world’s largest audience of steroid users, aspirin and various types of painkillers occupy almost the first places for the reasons for people visiting and hospitalizing people with symptoms of an overdose of these drugs. Many of these cases are fatal.

Whereas requests for help from an overdose of AS occur in isolated cases. And they only concern the side effects that have arisen. Not a single case of death from an “overdose” of AS has been recorded in the world.

In principle, an “overdose” of ACC, a word that I would not like to use when describing AS, since an “overdose” of a “propic” only entails a greater frequency and the likelihood of “catch” one or another “side effect”. Toxic damage to the body does not occur in the event of an “overdose”.

Based on what was written above, it becomes clear that the problem of the harm of testosterone propionate, and steroids in general, is greatly “inflated” and does not correspond to reality.

I'm not trying to say that testosterone propionate doesn't have side effects, it does. But in the vast majority of cases, using propionate in recommended dosages, you won’t even notice them.

But if side effects do occur, almost all of them are reversible and can be controlled with the use of appropriate medications. The exception is advanced cases of gynecomastia, when cosmetic surgery to remove it is necessary.

Possible side effects from the use of testosterone propionate

• aromatization - the conversion of testosterone under the action of the aroma enzyme into estradiol and the possible subsequent development of estrogen-related side effects - gynomastia, accumulation of water, deposition of fatty deposits.

Aromatization is easily removed by the use of anti-aromatase drugs such as anastrozole.

When using testosterone propionate, aromatization is practically not expressed due to the short period of action of the steroid in the body.

Aromatization is not evil; aromatization increases the effectiveness of the AC course, since estrogens stimulate the production of IGF 1.

Aromatization “becomes evil” when the balance of sex hormones shifts towards estrogen. Estrogen levels are monitored using tests. But if you use propik, you most likely will not need them.

There is no need to specifically take aromatase inhibitors, in particular buy anastrozole, and “kill” estrogen to zero; take them only if side effects occur.

If you are wondering whether there is a negative effect of propionate on the liver, kidneys, gastrointestinal tract, heart, then there are no such negative effects!

As for the effect on the genitourinary system:

Many people are interested in whether they will become impotent while taking testosterone propionate. They won't. On the contrary, during the course your libido will increase and you will feel like a “super man”.

Since test propionate quite strongly suppresses the production of your own testosterone, after the course you may experience a slight drop in libido. In my practice, this only happened in the case of very long courses with large dosages of AC. By taking short courses on propionate - 6-7 weeks, you will most likely not even feel a drop in libido. Having carried out competent PCT, libido will quickly return to normal. Moreover, after the course, and taking tests, before the start of the course and after PCT, I more than once observed an increase in the level of my own testosterone, to values ​​greater than it was before the course.

Action of testosterone propionate[edit | edit code]

Concentration in the blood after injection of 50 mg Concentration fluctuations when administered 2 times a week

• It specifically initiates gene transcription, thereby changing the nitrogen balance in a positive direction.[9]
• Increases levels of insulin-like growth factor in muscles and liver[10]
• Causes proliferation of satellite cells in muscle tissue[11], due to which hyperplasia and muscle restoration occur

It should be noted that all esters have the same mechanisms of action, the difference lies in the activity and primary direction of action.

Effects[edit | edit code]

• Increased muscle mass
• Increased relief
• Increased strength indicators
• Increase libido
• Reducing the risk of cardiac ischemia and coronary disease[12]

It has a short duration of action. Injections are usually performed every other day. This is one of the main disadvantages of using propionate, compared to its longer-lived analogues, for example, enanthate. The second main disadvantage is the higher cost compared to the same enanthate. Can be used both when working on ground and during the drying period.

It is worth noting that the short action of the drug may be a plus. The fact is that each body is individual and reacts to the drug differently. There are cases of intolerance to the components of the drug (usually to the so-called solvent - oil, which contains testosterone), which may be accompanied by an allergic reaction. Due to the fact that this drug is quickly absorbed, an allergic reaction (if one occurs) can also pass relatively quickly without causing serious harm to the athlete’s health[13].

Another feature of the drug is that with correctly selected dosages, most athletes do not retain water in the body or these manifestations are minimal. Therefore, testosterone propionate does not cause a sharp increase in body weight by 5-6 kg in a couple of weeks, as when using the same enanthate, but the muscle mass gained using propionate will be leaner and of better quality. Once in the body, it is quickly absorbed into the bloodstream, so the work of propionate can be felt after the first injection. And it comes out just as quickly. For the above reasons, when working on mass, athletes prefer enanthate, and propionate is more often used when cutting. Suitable for athletes of any level, from beginners to the most experienced.

How long is testosterone propionate excreted and effective?

“Propik” begins to act in the body almost immediately after the injection. Maximum activity is achieved within the first 24 hours after an injection of testosterone propionate, followed by a decline within two to three days.

Thus, the half-life of this steroid is 1-2 days.

In fact, if we talk about the elimination of the drug, in terms of the time when you need to start PCT, then PCT after propionate can and should be started after about three half-life periods - about 6 days after the last injection.

If we mean doping - monitoring for the presence of propionate metabolites in the blood, then detection of such metabolites is possible within a period of 40 to 60 days.

So, if you expect that you will need to undergo doping control, you should stop using propionate two months before the expected test.

Very often, people ask if taking propionate will affect my CBC, can doctors detect that I'm taking steroids?

Answer - No, they cannot.

A complete blood test cannot show that you are using any steroid drugs.

PCT after propionate

The duration of PCT after using propionate will primarily depend on the duration of the course. For PCT, the following rule applies: the duration of PCT depends on the duration of the course. This means that if your course lasted 6 weeks, then PCT should be done for 6 weeks.

We have already written above about how long it is necessary to start PCT after the last propic injection. This is the time when the steroid is completely eliminated from the body. Complete removal of “propik” usually occurs 6-8 days after the last injection. As a rule, after such a period, you can expect that testosterone levels have dropped to about zero values.

In order to accurately determine the level of total testosterone, we highly recommend

take tests for total testosterone and estradiol. An analysis of estradiol levels is needed in order to “bring down” the latter, provided that the indicators are inflated. Elevated estradiol levels will interfere with recovery in the same way as elevated testosterone levels. Recommended total testosterone values ​​for starting PCT are 5-6 nanomoles or lower.

After the level of exogenous testosterone has dropped to the required values, it is necessary to begin PCT with antiestrogens. Preference for PCT is given to buy Clomid. Clomid is a more modern drug that has fewer potential side effects than tamoxifen. Although many athletes whose budget is limited prefer tamoxifen to Clomid, due to the higher cost of the latter. By and large, in terms of the strength of their effect on the restoration of the “arc of the HPA,” the drugs are equal.

Let us give an example of the dosage of Clomid after a 6-week course of propionate, which can be described as a “moderate course”. For the first 30 days you take 50 mg of clomiphene, the next 15 days 25 mg. At this point the PCT can be considered completed.

If you have a budget, it’s not a bad idea to get tested for basic sex hormones to determine how complete the recovery was.

Course design[edit | edit code]

It can be the only steroid in a “cycle”, but the best effect is achieved when combined with other drugs. Athletes starting to use anabolic drugs can recommend dosages of 50 mg of propionate every other day. The usual dose for more experienced athletes is 100 mg propionate daily and above.

Be sure to take anti-estrogenic drugs, such as Proviron or aromatase inhibitors, according to the standard regimen, starting from the second week to avoid the development of gynecomastia, fluid retention and other estrogenic effects. After completion of the administration, post-cycle therapy is carried out, most often tamoxifen is used. It is also advisable to take cortisol blockers at the end to maintain the gained weight. Be sure to follow a weight gain diet and take sports nutrition.

Combined course[edit | edit code]

When drying, it combines well with stanozolol, trenbolone acetate, Masteron, Primobolan and some other drugs. Propionate is included in mixtures of testosterone esters such as sustanon or omnadren, as an essential component that allows you to immediately feel the work of the steroid.

An example of a cycle for beginner “chemists” for propionate-based drying:

• Propionate 50 mg every other day
• Winstrol 30 mg per day, starting with 10 mg, and increasing the dose to the optimal dose over 1 week.
• After 6 weeks, anabolic agents should be discontinued and PCT should be started 3-4 days later.

This course demonstrates the synergistic effect of the drugs, meaning that the total effect of their simultaneous use is greater than the simple sum of the effects if they were used each separately. Some experienced athletes use local injections of propionate into the target muscle, such as the biceps, deltoids, and calves when working on mass, but this approach has not been proven to be effective.

Any form of steroid has only a resorptive effect, with no local effect on the muscle. If the drugs, when administered intramuscularly, stimulated local hypertrophy of these muscle cells, then asymmetrical growth could be observed, outwardly similar to the results obtained with the use of synthol.

How and how much to inject (take) testosterone propionate?

The period of effective action of propionate is one day, which means: you must inject propionate at least every other day.

Ideally, you should inject propic every day, which is, to say the least, inconvenient. After all, not everyone is ready to “punch” their ass every day. And what's the point?

To gain muscle mass, it is much more convenient to use any of the long-lasting testosterone esters - enanthate, cypionate or testosterone mixes (sustanon).

Propionate is injected mainly into the large muscles of the body - the gluteal, thigh muscles. Less commonly, testosterone propionate is injected into the deltas.

For injection into the gluteal muscles, it is best to use 5 ml syringes, as they have a long needle, which ensures that the oil gets deep into the muscle. For injections into the deltas and thighs, 2 ml syringes are mainly used.

By the way, few people know that propionate can be administered subcutaneously, i.e. into the fat layer on the abdomen. To do this, use an “insulin” syringe.

The recommended basic dosage of propionate for beginners is 50 mg, every other day or every day. Experienced athletes use 100 mg. every day and above. You can calculate how much propionate you need to inject per week depending on body weight using a simple formula:

The starting dosage of “propik” for beginners is 5 mg for every kilogram of weight. Maximum 9 mg. If your weight is, for example, 80 kg, then your “starting” dosage will be: 80*5 = 400 mg per week.

Side effects of propionate[edit | edit code]

The most common complaint is pain, irritation and redness at the injection site, which is further aggravated by the high frequency of injection. Marked increase in aggression.[14]

The side effects of testosterone propionate are due to the fact that it easily aromatizes and is converted into estrogens and dihydrotestosterone, like any other testosterone ester, at high dosages it can cause:

• Gynecomastia
• Acne
• Baldness of the scalp
• Hirsutism (body hair growth)
• Prostate enlargement (especially in older people)
• Masculinization (in women)

The drug suppresses its own production of testosterone, which is usually restored at the end of the course after 2-3 months. For long-term courses, it is necessary to administer gonadotropin 500 IU, once a week, starting from 2. As practice shows, in moderate doses it does not affect the liver, kidneys, or any other internal organs. Not recommended for use by women due to high androgenic activity.

Read more:

Side effects of steroids and how to reduce harm

Publications in the media

(Testosteroni proplorras)

Synonyms. Oreton F.

Composition and release form. 1% and 5% oil solutions of testosterone propionate in 1 ml ampoules.

Indications. Sexual underdevelopment in men, delayed puberty, functional disorders in the genital area; breast and ovarian cancer in women; dysfunctional uterine bleeding; acromegaly.

Pharmachologic effect. Testosterone propionate is a synthetic analogue of the male sex (androgenic) hormone. Androgen secretion is regulated by gonadotropins. Androgens are responsible for stimulating spermatogenesis, the development of secondary sexual characteristics in men and the completion of puberty. Androgens are highly lipid soluble and penetrate target cells by passive diffusion. Under the influence of the enzyme 5-alpha reductase, testosterone in target cells is converted into 5-alpha-dihydrotestosterone. Testosterone and 5-alpha-dihydrotestosterone, through binding to cytosolic androgen receptors, initiate transcription in the cell nucleus, resulting in increased protein synthesis. Testosterone propionate, in addition to its specific androgenic effect, affects nitrogen and phosphorus metabolism. Thus, the drug has an anabolic effect.

Pharmacokinetics. Testosterone propionate is slowly absorbed from the injection site, but is more persistent in the body than testosterone. The connection with plasma proteins is high - 90-98%. Metabolized in the liver, excreted mainly in the urine in the form of metabolites.

Side effects. Women only: amenorrhea or oligomenorrhea, virilism; only in men: bladder irritation, urinary tract infections, breast tenderness, gynecomastia; swelling; erythrocytosis or polycythemia; nausea, vomiting, liver dysfunction.

Contraindications. Breast cancer in women; prostate cancer; increased sensitivity to androgens.

Adverse reactions when interacting with other drugs. When used together, indirect anticoagulants and testosterone propionate may increase the anticoagulant effect by reducing the concentration of the procoagulant factor in the blood. Androgens can reduce blood glucose concentrations, so to avoid hypoglycemia, it is necessary to adjust the dose of insulin when administered simultaneously. Androgens increase plasma concentrations of cyclosporine when used together, increasing the risk of nephrotoxicity.

Information for the patient. Oily solutions of testosterone propionate are administered intramuscularly or subcutaneously, the dose is selected individually taking into account the nature of the disease. Treatment is usually carried out over a long period of time; when the clinical picture improves, switch to maintenance doses.

Notes[edit | edit code]

1. Korenchevsky V, Dennison M, Eldridge M (1937). "The prolonged treatment of castrated and ovariectomized rats with testosterone propionate." Biochem. J. 31(3):475–85. doi:10.1042/bj0310475. PMC 1266958 Freely accessible. PMID 16746360.
2. Eberhard Nieschlag; Hermann M. Behre; Susan Nieschlag (26 July 2012). Testosterone: Action, Deficiency, Substitution. Cambridge University Press. pp. 9.315–. ISBN 978-1-107-01290-5.
3. William Llewellyn (2011). Anabolics. Molecular Nutrition LLC. pp. 357–361,413,426,607. ISBN 978-0-9828280-1-4.
4. Pushkar D. Yu., Segal A. S. Modern possibilities for correcting age-related androgen deficiency in men // Effective pharmacotherapy. – 2010. – No. 32. – pp. 16-21.
5. Eberhard Nieschlag; Hermann M. Behre; Susan Nieschlag (13 January 2010). Andrology: Male Reproductive Health and Dysfunction. Springer Science & Business Media. pp. 441–446. ISBN 978-3-540-78355-8.
6. Behre HM, Abshagen K, Oettel M, Hübler D, Nieschlag E (1999). "Intramuscular injection of testosterone undecanoate for the treatment of male hypogonadism: phase I studies." Eur. J. Endocrinol. 140(5):414–9. doi:10.1530/eje.0.1400414. PMID 10229906.
7. Bayramov A. A., Kuznetsova N. N. Androgen-dependent influence of the m-anticholinergic metamizil on the bioelectrical activity of the brain // Psychopharmacology and biological narcology. – 2006. – T. 6. – No. 1-2.
8. https://www.fitnessuncovered.co.uk/performance-drugs/profiles/testosterone-propionate
9. J Clin Endocrinol Metab. 1997 Feb;82(2):407-13.
10. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E601-7.
11. Curr Opin Clin Nutr Metab Care. 2004 May;7(3):271-7.
12. Heart. 2004 Aug;90(8):871-6.
13. https://iron-set.com/farmakologiya/propik
14. Pope, H. G., Kouri, E. M., & Hudson, J. I. (2000). Effects of supraphysiologic doses of testosterone on mood and aggression in normal men: A randomized controlled trial. Archives of General Psychiatry, 57, 133-140

What should I take testosterone propionate with?

Testosterone propionate is a universal, basic ester; in fact, it (or its “long-living” relatives) should be the basis for any combined course.

Combining it with other steroids is so widespread that there is no point in presenting all possible options within the framework of this article.

The only thing I would like to say is that propionate is not combined with other testosterones and testosterone mixes, for example sustanon. Why?

Yes, because the difference between these broadcasts is only in the duration of operation of one or another broadcast. The effect of application will be the same. And an increased dosage of androgens is likely to lead to side effects.

You can start taking propionate at the beginning of the cycle, for example, with testosterone enanthate, so to speak, for “loading”, until the long ester starts working at “full” power, followed by two weeks after the start of the course. Well, as mentioned above, it is also worth taking the drug as an “exit” from the cycle after long testosterone esters.

We will consider in detail the question of what you should take testosterone propionate with during a course separately, using the example of ready-made courses based on this steroid.

Combining propionate with other anabolics

Propic is rarely taken on its own, as it is much better used in combinations. Let's talk today about the most popular ones.

A course of turinabol and testosterone propionate

The combination of testosterone with turinabol is an excellent option for those who want to take their first course of steroids without losing testosterone during this period and still get more effect than from a solo course. And for those who have already completed a solo course with turinabol or other anabolic steroids and realized from their own experience that it’s time to combine these drugs and not turn their noses up, since the general condition without testosterone is somehow not particularly pleasing and they should repeat this experience already I don't really want to.

Simply put, if you do not have knowledge and experience, but you still decide to do a course of steroids and do it yourself, then the most suitable and successful option for each of you is to take a course of turinabol with testosterone propionate, since such a course is easier to administer and with This can lead to fewer problems. In addition, this combination can be used both for the purpose of gaining and for cutting with properly selected nutrition and training.

If we take into account the first experience, then in this case it is worth stopping at 6 weeks of the course as acquaintance and training. Propik can be taken three times a week, 100 mg, but better every other day, and Turinabol should be taken 30-40 mg. every day in 3-4 doses of 10 mg. It is better to take the tablets on an empty stomach if there are no digestive problems, otherwise take them with or after meals. After such a course, it is necessary to undergo therapy (PCT), tamoxifen is suitable for this, but it is better to stick with Clomid.

Masteron and testosterone propionate course

A combination with Masteron is used more often during a cutting cycle, but even with experience, this drug shows itself well for gaining lean muscle mass, but in this case higher dosages are used and the length of the course also increases. Despite the fact that the substances belong to the same group, they have different steroid profiles, so they complement each other perfectly.

Injections can be done in one syringe, since oil preparations can be mixed. Injections should be performed every other day, and the starting dosage of the substances is 100 mg of each. If the combination is used for cutting, the result will depend on how you eat and exercise. In general, you can focus on a couple of months with the goal of losing 10-20% of your weight without losing muscle mass. PCT after such a course can be done on tamoxifen or Clomid, and during the course I recommend using gonadotropin according to my scheme. PCT and gonadotropin regimens are available on the website in the “Health” section.

Course of propionate and stanozolol

The combination is used more for relief, since stanozol practically does not retain water, but at the same time accumulates protein well in tissues, which serves as a good catalyst for nitrogen in the muscles, which gives the effect of venousness and muscle fullness.

If there are problems with the gastrointestinal tract, then Stanozol can be replaced with injectable Winstrol, but this drug is much more expensive. In terms of effectiveness, Winstrol and Stanozolol are the same, they differ only in that Winstrol injections have greater bioavailability and bypass the digestive system, but the frequency of use of the drugs remains the same. The course should be extended over 6-8 weeks. Testosterone is administered in a dosage of 100 mg. every other day, and stanozolol should be taken every day, 30-40 mg. fractionally The dosage of the oral version is divided into 3-4 equal doses, and it is advisable to perform Winstrol injections twice a day, 20 mg. Tamoxifen or Clomid are suitable for PCT.

The choice of bundle depends on your goals. The main thing is to remember that side effects can occur in both men and women, so never prescribe medications yourself; before taking and during a course of steroids, consult a specialist, take the necessary tests so as not to harm your body.

Properties of the drug

Testosterone propionate in its properties differs little from any other type of Testosterone, with the exception of the release rate and half-life. The structure of the drug is virtually no different from the natural hormone produced in the human body and most animal species. Due to this, Testosterone is considered the safest steroid to use, since every person's body is accustomed to the effects of Testosterone, albeit in smaller quantities.

Testosterone has moderate estrogenic activity and a moderate affinity for the aromatase enzyme (responsible for converting Testosterone into estrogen). Accordingly, a moderate level of aromatization should be expected when using Testosterone, unless an aromatase inhibitor (for example, Arimidex, Aromasin or Letrozole) that blocks the conversion of Testosterone to estrogen is also used. Therefore, Testosterone is preferred as a means to build muscle mass, but it can also be used in the “cutting” phase and burning fat. Ultimately, the use of one type of Testosterone is required during any anabolic steroid cycle, at least to maintain the physiological function of Testosterone in the body during the period when endogenous production of the hormone is suppressed or stopped due to steroid use. Testosterone also has a very strong anabolic effect and can be used on its own.

Among athletes and bodybuilders, there is an opinion that Testosterone propionate is the best version of Testosterone for use in the “cutting” phase and burning fat. Many claim that it retains fluid in the body to a lesser extent than other esterified forms of Testosterone. Such statements do not have any scientific basis. As explained earlier, the propionate ester (or any other ester bound to Testosterone) is always separated by enzymes in the body, leaving behind 100% pure Testosterone. This testosterone, identical to the natural hormone, can freely perform its function in the body, and this applies to any esterified forms of the hormone. Thus, the only possible change associated with the addition of an ester relates to the half-life and release rate. Obviously, there should be no other differences when using different forms of Testosterone, or they will be minimal, since only the amount of hormone released into the bloodstream at any given time depends on the added ester.

Stanozolol and testosterone propionate: what to drink after the cycle

The main factor that will influence what remains after the course is the correct post-course therapy. The regimen for using antiestrogens and their quantity depends on the length of the course and the anabolic steroids included in it. If you need help in drawing up a PCT, write through contacts. Great news for you: I will draw up a PCT scheme for free (as well as preparatory preparation for post-cycle recovery) if you have become a victim of an illiterate specialist (send correspondence with a consultant or a sketch via messengers). Be sure to use a vitamin-mineral complex, one of which I mention in this article. Reduce your load, eat right.

Additional drugs on the course: testosterone propionate and stanozolol (Winstrol)

Aromatase inhibitor (for example, anastrozole), prolactin inhibitor (cabergoline), hCG (cases of use), Clomid - for rehabilitation therapy. We need anastrozole to promptly adjust the concentration of estradiol, an increase in which leads to (excessive) water retention, female-type fat gain, decreased sexual desire, sluggish erection, and the appearance of gynecomastia. Cabergoline is needed to control prolactin, an increase in which leads to unwanted side effects such as: gynecomastia, increased blood pressure, decreased libido and erection. The dosages of the above drugs are selected based on test results . Companies that are in demand: Balkan Pharmaceuticals, ZPHC, UltraPharm, . This does not mean that other manufacturing companies are not worthy of attention, I just have confidence in the above companies.

What we will need for the course:

1. Testosterone propionate 21 ampoules (or 2 bottles of 10 ml each)
2. Stanozolol 168 tablets (based on 4 tablets per day of use)
3. Anastrozole 20 tablets 1 mg each
4. Cabergoline 2 tablets 0.5 mg each
5. Clomid (Clostilbegit) minimum 30 tablets of 50 mg
6. HCG (optional)
7. Pharmaceutical preparations (flamin, etc.)

This amount is designed for a six-week, full-fledged steroid cycle, followed by rehabilitation therapy.

In fact, this is a competent and complete list of what we will need for the course; there is no need to save money or cross out any number from the proposed list. Anastrozole, cabergoline, Clomid (clomiphene citrate) - can be purchased at the pharmacy, a prescription may be required. Stanozolol in this course can be replaced with masteron propionate; again, I will definitely write a separate article about this combination, because it deserves special attention.