HGH 176-191: how to take, side effects, compatibility, reviews

• November 4, 2018
• Sports nutrition
• Svetlana Funtova

For those who decide to get rid of excess fat deposits in the usual way (without surgery), experts advise using the HGH Frag peptide (176-191). Fitness trainers claim that this drug helps solve one of the significant problems for many women - preventing the occurrence of atrophy of adrenergic receptors in fat cells. The effect of this remedy is actively discussed on forums and it is noted that even bodybuilders use it. In the article we will tell you what HGH 176-191 is and how to take this drug.

How does this peptide differ from somatropin?

It is important to understand that HGH 176-191 Frag is not a growth hormone like somatropin. The chemical formula shows that this substance is an integral part of the GR amino acid chain, which combines one hundred and ninety units.

Compared to the positive properties of somatropin, this isolated part has a targeted fat-burning effect, thereby accelerating lipolysis. In addition, the following effects are added to the listed effects:

• Rejuvenating effect.
• Increasing the energy potential of the body.
• Bone mineralization.

But the main difference and important advantage of the HGH Frag 176-191 peptide over somatropin is that it begins to act immediately after administration, while growth hormone takes time to accelerate. It is also important that this peptide in no way affects insulin production.

The mechanism of fat burning and the role of the peptide in it

The process of fat burning in the human body occurs through the breakdown of fats in the mitochondria. Fat cells get there as a result of interaction with carnitine. The speed of the lipolysis reaction and its effectiveness depend on the following indicators:

• Presence of stress.
• The presence of psychological discomfort.
• State of the central nervous system.

These factors directly or indirectly influence the production of adrenaline, which is responsible for the proper functioning of adrenergic receptors. One of them (β3) is located in adipose tissue and controls the process of breakdown of its cells. It is the functioning of this receptor that is affected by HGH peptides 176-191.

Research by scientists has established that isolated fragments of somatropin repeatedly increase the concentration of adrenergic receptors, causing better and faster lipolysis.

Price

The price of peptides required for a weight loss course depends on your weight at the time of use and the type of substances. Cost of peptides for weight loss depending on weight category:

Since “cocktails” of peptides are often used, the price can increase significantly when using a mix of several substances.

Effects produced by the fragment

Despite the fact that the peptide is just an isolated fragment from the chain of amino acids of growth hormone, it can have a significant effect on the body. To get the predicted effect, you need to know how to take HGH 176-191.

In most cases, a peptide is expected to:

• Active burning of the fat layer.
• Accelerated recovery processes after completion of active training.
• Strengthens bone tissue, which significantly reduces the risk of developing osteoporosis.
• Rejuvenating effect on the body.
• Increased performance even in limited nutrition mode.
• Optimizing blood sugar levels by reducing the effect on insulin concentrations.

It should be borne in mind that the drug acts on the adrenergic receptors of fat cells, so the best result can be obtained in case of insufficient calorie intake into the body. It follows that it is advisable for people using HGH peptide to exercise and follow a diet.

The substance finds practical application in the fitness industry. Since it is impossible to build muscle mass with its help, the product is used to dry the already gained volumes. In other words, the peptide is used by athletes to give muscle definition, especially by participants in fitness bikini competitions.

Effect on the body

HGH Frag 176-191 peptide affects the body as follows:

• Promotes fat burning. However, the drug gives a weight loss effect only if you reduce your calorie intake. Therefore, while using the product you need to adhere to a certain diet.
• Increases the effectiveness of training. The drug also helps the body recover faster after exercise by increasing physical endurance.
• Positively affects the condition of the musculoskeletal system. This reduces the risk of osteoporosis and other similar pathologies.
• Improves the condition of the epidermis and has a rejuvenating effect.
• Increases performance. Even despite the reduction in calorie consumption, the body receives a full charge of energy. Thanks to this, performance does not decrease, but increases.
• Normalizes the concentration of glucose in the blood.

Taking the drug

The question of how to take HGH 176-191 interests many novice athletes. You need to know that the main condition is subcutaneous administration of the drug on an empty stomach. Beginners are scared of injections, but experts say that a great desire and willpower will help overcome the fear and difficulties of the regime.

The rules of admission provide for the first injection immediately after waking up in the morning and only after an hour and a half is food intake allowed. Next, injections are given between eating sessions at the same time intervals. It is the adherence to such a regime that causes difficulties for beginners, but only it can give the desired result.

On training days, the last injection is given half an hour before training, on other days - just before going to bed.

The course of HGH Frag 176-191 lasts up to twelve weeks. This is due to the fact that the body cannot be limited in the supply of nutrients for a long time. This is especially true for foods with a high glycemic index. They are vital for the functioning of all organs, but increase the concentration of insulin, which significantly reduces the effect of the peptide.

How to take it correctly?

The first injection of the drug hgh frag 176 191 is administered using an insulin syringe in the morning on an empty stomach. The daily dose is divided into several injections, which should not exceed 1000 mcg. Eating after administration of the substance is carried out after an hour. The same pattern must be followed during lunch.

The final injection must be administered 30-40 minutes in advance, on the day of training, before going to the gym or before bed. The course of taking the drug should be no more than 3 months. During the course of taking the peptide, you must adhere to a special diet to achieve the desired result.

IMPORTANT: FAILURE TO FOLLOW THE DIET AFFECTS THE PROCESS OF RECOVERY OF THE BODY.

Dosages used

As mentioned above, the regimen and proper administration of the drug play a major role in achieving the desired result.

It is important to know that the course should be started gradually. In the first days, it is necessary to evaluate the body’s reaction to the administration of the drug.

The average dosage is from 750 to 1000 mcg (for beginners - from 100 mcg) daily intake, which is divided into several doses. The duration of the course is from four to twelve weeks, which depends on what results you want to get.

An approximate schedule for taking HGH 176-191 is as follows:

1. On training days:

• An hour and a half before breakfast – 250 mcg.
• An hour and a half before lunch – 250 mcg.
• Half an hour before training – 250 mcg.

2. On days free from sports activities:

• An hour and a half before the morning meal - 250 mcg.
• An hour and a half before lunch – 250 mcg.
• Half an hour before going to bed – 250 mcg.

HGH Frag course (176-191)[edit | edit code]

Dosages of HGH Frag (176-191) from 100 to 1000 mcg per day, course duration 2-3 months. Injections are performed between meals to create the most favorable conditions for fat burning. The drug is diluted in an isotonic solution or in water for injection, which is purchased in pharmacies. For maximum effect, you should follow a weight loss diet and take enough protein.

Approximate regimen for taking HGH 176-191 on the day of training:

• 200mcg 1 hour before breakfast
• 200mcg 1 hour before lunch
• 200mcg 30 minutes before training

On rest days:

• 200mcg 1 hour before breakfast
• 200mcg 1 hour before lunch
• 200mcg before bed

Sometimes it is recommended to perform 5-6 injections during the day

In addition, you should note that, unlike other peptides, HGH Fragment 176-191 after dissolution has a short shelf life (approximately 1 week in the refrigerator).

Storage and preparation of the solutionedit | edit code

According to the recommendations of Y. Bombela, it is necessary to bring the vial temperature to room temperature and introduce the required volume of water for injection or bacteriostatic water (which should flow down the wall of the vial). Then stir using rotating or rocking movements (do not shake). The solution remains stable for 15-25 days in the refrigerator without freezing. The last number applies only to solutions prepared with bacteriostatic water.

DietEdit | edit code

When conducting a course with a fragment, it is very important to adhere to a low-calorie diet. It is known that after eating, the level of insulin increases, and insulin is a hormone that stimulates phosphodiesterase, which breaks down cAMP - a second messenger molecule, which inhibits the process of lipolysis (this is why it is important not to eat immediately after injections and other peptides), because

pulsating secretion of growth hormone (GH) occurs within 3 hours after administration, and only in the first hour of pulsation will insulin work, and for the remaining two hours will fat burning occur as a derivative effect of GH). That is why injections are performed between meals, on an empty stomach.

There is no need to worry about the catabolic process, since the result of lipolysis (the release of fatty acids) is the replenishment of energy reserves. In this case, catabolism is impossible. It is from these considerations that we can make a well-founded conclusion that GH is an anti-catabolic.

Preparation of the drug for injection

The step-by-step process of preparing a solution for injection looks like this:

1. Remove the bottle from the refrigerator and wait until the substance reaches room temperature.
2. Inject physiological solution into the container with the peptide using a regular syringe for injections in an amount of 1 ml per 2500 mcg of active substance and 2 ml per 5000 mcg.
3. When all the liquid has flowed down the walls of the bottle, mix the composition with gentle rotational movements until it reaches a homogeneous consistency.
4. Draw the resulting solution into an insulin syringe No. 100. This is very convenient for dividing into one-time injections.

Side effects

Some experts claim that no side effects were found when using the peptide (fragment 176-191). Others say the possible negative impacts have not been thoroughly studied.

Doctors note that due to the large number of injections, redness, slight itching and mild pain occur at the injection site.

It should also be noted that during the use of the drug there is no natural destruction of muscle tissue. This is explained by the fact that during lipolysis, the body’s energy reserves are replenished due to the breakdown of fats.

Compatibility with other drugs

The HGH 176-191 fragment showed excellent results in cases where it was used without additional means. However, three variations of the combination of this peptide with other substances have gained some popularity in the sports environment. The options, dosages and dosage regimens are as follows:

1. Tandem with liquid growth hormone. Used to build lean muscle mass and simultaneously burn fat. It is used mainly by beginner athletes who do not have a large amount of muscle mass. The course of treatment lasts for three months. A double effect of the duet is achieved - somatotropin promotes the growth of muscle tissue, and the peptide transforms fat into an energy depot. According to the scheme, 5 units are used daily. growth hormone and 1000 mcg of peptide, dividing the entire amount into four injections. Some people use a powder form of GH.
2. Trio: melanotan-2, peptide 176-191, GHRP-6 peptide. Used to increase strength during the muscle drying process. The combination of substances ensures that the body has energy potential for training, and due to the property of GHRP-6 to increase appetite, muscle mass gain improves. The course lasts eight weeks. Peptide injections are given simultaneously (176-191 - 250 mcg, GHRP-6 - 100 mcg) three times a day, melanotan-2 - 1 mcg per kilo of body weight once a day for twenty days.
3. Melanotan-2 bundle, fragment 176-191, GHRP-2 peptide. Taking the drugs together increases strength, leads to the growth of lean muscle mass, promotes an even tan, improves appearance, strengthens joints and bones, and strengthens the immune system. The course lasts two months. Peptide injection regimen - (176-191 - 250 mcg, GHRP-2 - 100 mcg) three times a day, melatonan-2 - 1 mcg per kilogram of body weight once a day for three weeks.

Sources[edit | edit code]

1. Ng FM, Sun J, Sharma L. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res. 2000;53(6):274-8.
2. https://www.news-medical.net/news/2004/12/16/6878.aspx
3. https://elive.com.ua/dana-borisova-podelilas-sekretom-poxudeniya/
4. Heffernan M, Summers RJ. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001 Dec;142(12):5182-9.
5. Heffernan MA, Thorburn AW. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. Heffernan MA, Thorburn AW, Int J Obes Relat Metab Disord. 2001 Oct;25(10):1442-9.
6. Heffernan MA, Thorburn AW. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. Heffernan MA, Thorburn AW, Int J Obes Relat Metab Disord. 2001 Oct;25(10):1442-9.
7. Dr. Daniel Rudman's study in the New England Journal Of Medicine
8. Effects of oral administration of a synthetic fragment of human growth hormone on lipid metabolism MA HEFFERNAN, WJ JIANG
9. Professor Marc Grynpas and Dr Rita Kandel at the Samuel Lunenfeld Research Institute, Mt Sinai Hospital in Toronto, Canada 2011

Reviews about the peptide

Most reviews say that HGH Frag 176-191 has a positive effect on burning subcutaneous fat. It is also indicated that while using the drug, a diet with a reduced amount of carbohydrates was followed.

Some reviews concern taking the peptide in combination with other drugs. Athletes note that such courses produce a much stronger effect. This is especially true for newcomers to the world of athletics. They indicate that the product really begins to work from the very first days of use. According to their reviews, results can be observed after two weeks of use.

You can also often hear that the expected irritation at the injection site is not observed, and the injections are well tolerated by the body.

There are also negative opinions. Some bodybuilders claim that the effect of this peptide is similar to growth hormone, which does not give the desired results.

What should the diet be like?

The diet should be low in carbohydrates, as their consumption stimulates the body to produce the hormone insulin in order to distribute glucose to the right cells. This hormone is known to completely block fat burning. This is why you should not consume foods containing carbohydrates after injecting HGH Frag 176-191. It is necessary to include more proteins and fats in the diet to provide the body with the necessary micronutrients to build muscles and maintain the body in good condition.

In addition, HGH Frag 176-191 blocks catabolism - the destruction of muscle fibers. This is explained by the large amount of energy that is generated during the breakdown of fatty acids.