Date of publication: 06/23/2017
It is generally accepted that a course of Deca Testosterone Enanthate effectively accelerates the growth of muscle mass and increases the level of physical characteristics such as strength and endurance.
Both steroids in this cycle are used in injection form. But there is a difference between them in their anabolic activity: testosterone has androgenic activity, while dequinandrolone has anabolic activity. They are ideally combined when taken simultaneously.
Historical excursion
Nandrolone (19-testosterone), classified as an anabolic steroid, was synthesized in the fiftieth year of the last century. The structure of all anabolic androgenic steroids is similar to the structure of testosterone (male sex hormone). However, artificial analogs are much better at building muscle mass (anabolic effect). Nandrolone is a classic representative of anabolic steroids. Conducted studies have proven that in terms of the time of action on cellular receptors, which play an important role in the course of anabolic processes, it is superior to substances with a similar formula. This was the reason for the success of nandrolone. In Hungary, nandrolone decanoate was produced under the name "Retabolil". In the US and Western countries it is known as Deca-Durabolin. One ampoule of retabolil contains fifty milligrams of the active substance. The effect after using nandrolone lasts two weeks. The properties of nandrolone determine its use in recovery from injuries, treatment of dystrophy, in the postoperative and post-infarction periods. When the drug enters the female body, an increase in hemoglobin and a decrease in calcium loss from bone tissue are observed. For people whose activities involve constant physical activity (circus and ballet performers), a busy work schedule (show business stars), a course of injections is sometimes simply necessary and becomes a way out of a difficult situation. Many doctors, biologists, and physiologists consider the concept of the IOC (International Olympic Committee), which has declared a real war on doping, to be incorrect and, to some extent, criminal. The fact is that the prohibition of nandrolone by this organization, which supposedly guards the health of athletes and fair competitions, leads athletes to search for alternative options, which consist in the use of little-studied drugs that are more toxic and harmful to health.
History of the creation of nandrolone
Nandrolone was created for the purpose of its use in medicine as an additional drug in the treatment of osteoporosis, breast cancer, dystrophy, severe injuries, growth retardation in children (pituitary dwarfism), some forms of anemia, as well as exhaustion (in order to preserve muscle mass in seriously ill patients, where as a result of the course of the disease there is a loss of muscle mass and destruction of other building tissues (oncology, HIV)). Nowadays, nandrolone is approved by the FDA only for the treatment of anemia and unofficially in therapy to preserve muscle mass in seriously ill patients.
The history of the appearance of the drug occurred in the second half of the twentieth century, where in 1962 it began to be sold under a prescription. The developer of this drug turned out to be the pharmaceutical company Organon, which at that time created many other testosterone derivatives, as well as testosterone itself in particular. The first form of release of nandrolone was a dosage of 50 mg/ml, but quickly enough the need for a higher concentration arose, where the drug quickly went on sale at 100 mg/ml, and even later Organon released the drug at 200 mg/ml.
Today, nandrolone remains a widely available drug that can be purchased everywhere under numerous trade names, and it is also available officially by prescription and is used in pharmaceutical and veterinary practice.
Nandrolone can be easily found on the black market in countries where anabolic steroids are unfairly prohibited for open sale and are found under many trade names, but the top manufacturer still remains Balkan Pharmaceuticals and its subsidiary SP Laboratories, which is often counterfeited.
Properties of nandrolone
The structural difference between nandrolone and testosterone is the absence of methyl group 19 in the first molecule, which became the reason for the spread of the name 19-nortestosterone. This gave the substance the ability to better stabilize androgen receptors. In other words, the duration of action of nandrolone increases approximately two to three times compared to the duration of action of testosterone, and the longer the receptor remains activated, the more protein is synthesized by the cell. There is also a negative point: free nandrolone degenerates into dihydronandrolone (DHN), which is two to three times less effective than nandrolone, impairs the ability of nerve fibers to transmit signals, which negatively affects neuromuscular stimulation and libido. True, nandrolone is not so active in the prostate and skin, so athletes taking this drug are less susceptible to acne, prostate hypertrophy, and baldness.
The effect of aromatase on the course of nandrolone is not so significant. But as a result of a chemical reaction, estrogen is still produced, albeit in small quantities. We should not forget about the progestogenic activity of 19-nortestosterone. Those whose total dose of the drug exceeds six hundred milligrams per week put themselves at risk of developing gynecomastia.
Nandrolone in bodybuilding – features
The use of nandrolone for men and women will be different, including differences in a number of side effects. If you do not take into account the peculiarities of the drug and health indicators before the course, then the likelihood of getting a negative reaction during the course is greater.
Nandrolone is specific in its own way and its use still requires special knowledge, of course, if the goal of its use is to get the maximum with a minimum of problems. So, for example, when using it “at random - according to schemes”, several cases can be identified where, as an exception, the use of nandrolone will not cause significant trouble even if you neglect health control during the course, and the drug itself will be very successful and will provide sufficient positive effect. For others, the very result of using nandrolone may be barely noticeable, or even the specifics of its effect on the body will have a more negative effect than a positive one.
But the whole point is in the same 5-alpha reductase and in the individual characteristics of the organism, in which the level of reductase can be higher/lower. Where higher it is very bad, lower it is still tolerable. Since 5-alpha reductase converts nandrolone into a weaker androgen, this leads to suppression of signals along nerve fibers, which causes a weakening of neuromuscular stimulation and blunting of communication between muscle fibers, where metabolic processes deteriorate accordingly. And in practice, it turns out that we cannot take full advantage of all the anabolic capabilities of nandrolone, since we lose the interaction of muscle tissue with receptors, which in turn does not contribute to more effective muscle growth and strength indicators. This effect occurs in cases where a deficiency of dihydrotestosterone occurs in the cells, which is individually replaced by more/less dihydronandrolone. This indecency can be eliminated by adjusting the dosage of testosterone and using DHT derivatives.
But such resort to excess androgens does not always work or be suitable everywhere. It is no secret that an increase in the level of androgens, which are not converted into dihydronanodorolone, causes a number of adverse reactions and complications associated with their increased activity among men and especially women. Each case must be considered individually.
The peculiarities of nandrolone, as well as cases of the appearance of any abnormalities in hormones and the occurrence of adverse reactions, should not be a reason to refuse it or stop the course. All you need is timely, competent help. Of course, when the majority do courses from scratch, relying on tips from forums, which is dubious help, this is a risk and it is better to stop such an experiment if troubles arise. It’s another matter when there is someone to turn to for specialized help, where timely adoption of measures before the course helps eliminate all its shortcomings. And in the event of the development of any adverse reactions during the course, medical intervention to help and a number of measures that will help ensure that the course of steroids is successful and with the greatest result. Therefore, in order not to guess the body’s reaction by your own example, and not to waste the course down the toilet with the help of all sorts of tips from forums or gyms, control of the body is still required and especially specialized attention during the entire course of steroids.
Application
The choice of method of administration of the drug is determined by genetic differences. For some, nandrolone is simply a miracle cure. Others, whose body does not interact well with the “long esters” of nandrolone, risk developing health problems. This result is due to the presence of a large amount of 5-alpha reductose in muscle fibers, when it is possible to replace 19-nortestosterone with phenylpropionate, or increased sensitivity to progesterone. In the second case, the way out is to use nandrolone together with stanazolol or to prevent the weekly dose from exceeding three hundred to four hundred milligrams. For athletes who do not have the characteristics described above, the use of nandrolone will greatly facilitate weight gain. The purpose of testosterone and nandrolone is to activate satellite cells and increase IGF-1, stimulating muscle hyperplasia, but the dosage of the latter should exceed six hundred milligrams per week. Based on the properties of nandrolone, which can retain water, its use during “drying” before competitions is inappropriate.
Previously, there was an opinion that the retention of fluid in the body under the influence of nandrolone is one of the factors for the accumulation of water in the joint capsules, which is why the joints experience a beneficial effect. In fact, the mechanism of functioning of 19-nortestosterone is somewhat more complicated.
The drug does not cause an additional influx of water into the joint capsules. Thanks to nandrolone, water simply does not leave them. This process is explained by the fact that nandrolone is a very strong progestin, having a fifth of the power of progesterone, and can be converted into estradiol, which is responsible for retaining water in tissues. Assessing the properties inherent in nandrolone, one cannot fail to note its superiority over other drugs that have antiestrogenic (drostanolone) and antiprogestagenic (stanozolol) activity. Composing a cycle of trenbolone, stanozolol, drostanolone can cause harm to joints during intense training. Do not forget: if a certain concentration of estrogens and progestins is exceeded in the blood plasma, then an anti-inflammatory effect is observed. Nandrolone has progestogenic activity, the ability to convert into estradiol, which determines the possibility of a beneficial effect on joints. In this regard, nandrolone is significantly superior to oxymetholone, methandrostenolone, and testosterone.
Nandrolone not only affects the increase in muscle mass. When taking it, strength indicators increase significantly. Most athletes, whose weekly dose is at least four hundred milligrams, confirm this. True, there is one very important negative factor: the suppression of endogenous testosterone production by 19-nortestosterone leads to a deterioration in the conductivity of nerve fibers and impaired erectile function. Not everyone is ready to sacrifice their intimate life. The way out of the situation is seen in using some strong androgen, for example, testosterone, in combination with nandrolone.
Side effects
There are usually no serious side effects when using the deck. However, when the weekly dosage exceeds four hundred milligrams, it is not uncommon for blood pressure to increase. Against the backdrop of deteriorating blood clotting, this leads to nosebleeds, poor wound healing, overworking of the sebaceous glands, acne, and severe headaches. The maximum increase in dose is fraught with disruption of the testicles, which begin to produce less testosterone, which causes a delay in the release of gonadotropins by the pituitary gland.
The high progestogenic activity of nandrolone leads to erectile dysfunction and gynecomastia.
Nandrolone Decanoate
It is a popular injectable steroid in the world. The drug gained such fame due to the fact that it has high anabolic activity and virtually no side effects.
AS is natural and is present in every organism, but in small quantities.
The effect of this drug reaches 15 days. Dosage: 200-400 mg per week. Possible side effects:
- the appearance of acne and rashes;
- increased hair growth or, conversely, baldness;
- decreased libido levels;
- headache;
- back pain;
- nasal discharge;
- depression and irritability;
- stomach ache.
But such signs can only be observed in the case of a large increase in dose. This is quite a rare occurrence.
Positive effects from taking nandrolone: increases muscle mass up to 8 kg per course, minimal level of rebound, strengthens bones and ligaments, eliminates joint pain, increases red blood cell mass in the blood, improves immunity.
Detection time is up to 18 months.
Dosage methods
Achieving a noticeable effect from taking nandrolone is possible at dosages of two hundred milligrams per week and above. Some professional athletes prescribed a daily dose of eight hundred milligrams. How practical this is these days is difficult to say. Indeed, recently there has been a tendency to abandon nandrolone decanoate. World-class bodybuilders consider this drug to be exhausted and obsolete. However, people who do not think about sports achievements and simply want to have a beautiful body can be advised to set an upper limit for themselves of one gram of nandrolone per week.
Nandrolone decanoate has a fairly long half-life, so it is advisable to stick to one injection per week. True, there is another opinion. Many people believe that to maintain stable hormone levels, it is better to introduce long-lasting drugs into the body more often.
Testosterone Enanthan
One of the most common steroid drugs in bodybuilding. It is a complex variety of testosterone essential oil. It has a long range of action, which depends on the individual characteristics of the body (in particular, on the metabolic rate and hormonal levels).
The average period of action is 2-3 weeks. In order to maintain a high level of concentration of the substance in the blood, injections are given once a week.
It is worth noting that this testosterone should only be taken by professional bodybuilders. It is not recommended for women.
The dosage of the drug can vary from 250 mg to 1 thousand mg. If this norm is exceeded, the following symptoms may be observed:
- water retention in the body;
- the appearance of acne;
- high blood pressure;
- decreased level of secretion of own testosterone;
- it has a toxic effect on the liver.
How to combine Deca with other steroids
It’s not so often that you meet people who choose nandrolone as the only steroid in their cycle. Rather, this is the lot of testosterone and trenbolone. Usually drugs that are synergists are combined. The regimen of taking nandrolone with methandrostenolone is considered effective. Even greater effectiveness is achieved by those who include testosterone in the complex with nandrolone (the ratio of nandrolone to testosterone is 1:2). The second method is also a kind of insurance against problems with potency. A combination of the three drugs listed above is the best option for those who want to gain weight in the shortest possible time.
It is worth warning zealous followers of dubious ideas who take everything they are told on faith. The use of nandrolone with other progestins (anadrol, trenbolone) is dangerous and can lead to negative consequences and cause a long-term withdrawal from anabolic steroids.
Deca + Methane + Testosterone (enanthate, propionate)
Since Sustanon 250 is a mixture of testosterone esters, you can create a course using these esters separately. Its action will be similar to the previous course, but here you can change the dosage of testosterone yourself to increase efficiency.
1 week: methane 30 mg/day+deca 50 mg/week+testosterone enanthate 250 mg/week
Week 2: methane 30 mg/day+deca 100 mg/week+testosterone enanthate 250 mg/week
Week 3: methane 30 mg/day+deca 100 mg/week+testosterone enanthate 250 mg/week
Week 4: methane 30 mg/day+deca 100 mg/week+testosterone enanthate 250 mg/week
Week 5: methane 30 mg/day+deca 100 mg/week+testosterone enanthate 150 mg/week
Week 6: methane 30 mg/day+deca 50 mg/week+testosterone enanthate 150 mg/week
Week 7: methane 30 mg/day + testosterone propionate 50 mg/every other day
Week 8: methane 30 mg/day + testosterone propionate 50 mg/every other day
The dosages of the drugs presented here are optimal. By increasing dosages at your own risk without medical supervision, you significantly increase the likelihood of serious side effects. Increased dosages and long courses require the mandatory use of additional medications and the use of post-cycle therapy. Remember: thoughtless and inept use of anabolic steroids can lead to serious health problems.
Use of deck by women
In the middle of the last century, nandrolone found wide use in the treatment of women. Moreover, representatives of traditional medicine considered it a fairly effective drug. Then athletes paid attention to 19-nortestosterone and actively used it until the nineties, until studies conducted by Heinonen and Goossens cast a shadow on the drug. The first experiment involved women taking fifty milligrams of nandrolone decanoate every three to four days. As a result, half of the subjects began to experience the phenomenon of virilization. The second experiment did not lead to the same. True, nothing was reported regarding the magnitude of the doses. Of course, women taking one hundred milligrams of nandrolone decanoate per week raises questions, but limiting the dose to thirty milligrams administered once every two weeks can be considered acceptable. This fact was proven by an experiment that took place in 1996, when no virilization phenomena were recorded with a similar method of administration. Dear ladies who have nevertheless chosen Deca as a means to achieve their goal, I would like to advise not to rush to extremes and start with a dose of fifty milligrams once every ten days, gradually increasing it to seventy-five to one hundred milligrams in the same period of time. The first signs of virilization should be a signal to stop taking the drug.
Testosterone intake and the female body
Some female bodybuilders also take testosterone. This can cause hirsutism and virilization. Hirsutism is a phenomenon that is accompanied by increased hair growth in the chin, cheeks, upper lip, back and ears. These processes are often accompanied by an irregular menstrual cycle and acute acne. Taking Deca is contraindicated in women. It is worth replacing analogues of Deca with products with a reduced effect on the reproductive system.
Virilization is caused by increased androgen levels. There is a decrease in the timbre of the voice, the appearance of bald patches in the temple area, a change in the figure according to the male type, and rapid muscle growth.